RESEARCH TRIANGLE PARK, North Carolina, December 11, 2012 Precision BioSciences, Inc., a leader in the field of genome engineering, today announced the publication of the first genetically modified mammals using Precisionengineered meganuclease technology. In a paper published in The FASEB Journal entitled Generation of Rag1-knockout Immunodeficient Rats and Mice using Engineered Meganucleases,, for the first time, the application of DNE genome editing nucleases to generate rats with a desired gene permanently disabled or knocked-out.
This paper demonstrates the broad applicability and exquisite precision of our DNE technology for mammalian genome engineering,said Derek Jantz, Precision BioSciencesVice President of Scientific Development. We are thrilled that our collaborators at Centre National de Recherche Scientifique and genOway were able to utilize the technology to efficiently generate an important research model.
erful tool for site-specific genome editing,look forward to applying our technique towards the generation of greatly needed therapeutics, research and bioproduction platforms, and agricultural products.
About Precision BioSciences
Directed Nuclease EditorTM (DNE) technology enables the production of genome editing enzymes that can insert, remove, modify, and regulate essentially any gene in mammalian or plant cells.
Precision BioSciencesengineering challenges are solved. Precision has successfully utilized its DNE technology to create innovative products in partnerships with many of the worldagbiotech, and animal research firms. Internally, Precision is developing applications of DNE in biological production and human therapeutics. For additional information, please visit www.precisionbiosciences.com.
Precision BioSciences: Chelsea Lynam, phone: +1 919 314-5512