|AcademicJobsOnline.Org: an automated job application system created and operated by the Duke Department of Mathematics. AcademicJobsOnline.Org expands the service of the the American Mathematical Society’s MathJobs.Org, making it available to all other employers (academic, industrial or research) searching for job candidates with advanced degrees in other disciplines. (New disciplines will be added as needed whenever new employers sign up for the service.)|
|Advanced Liquid Logic (Acquired by Illumina, Inc.): nanoliter lab-on-a-chip powered by digital microfluidics.|
|Aerie Pharmaceuticals: developing new therapies for sight-threatening diseases of the eye.|
|Aldagen (acquired by Cytomedix): products for the identification of adult stem cell populations with initial focus on the treatment of CV and peripheral artery disease.|
|Aqueti: providing imaging systems to enable simultaneous, multiple, image processing tasks over panoramic scales. An array of hundreds of high resolution cameras produce panoramic streaming video and snapshots, while sub-arrays enable display and tracking of multiple regions of interest based on operator specifications./td>|
|Argos Therapeutics: an immunotherapy company developing new treatments for cancer, infectious and autoimmune diseases, and transplantation rejection, based on the biology of dendritic cells.|
|B3Bio: developing an entirely new class of medicines which employ small RNA molecules to precisely target individual cells and tissues.|
|Bio-gyali: developed proprietary microglassification technology that gently removes water from solutions of biologicals, like antibodies, enzymes, and therapeutic proteins. Microbeads can be used to protect and stabilize biologicals for storage, transport, and inclusion in a variety of drug delivery formulations.|
|Biomimetix: developing a new class of patented compounds for the treatment of various disease and health care treatment classifications including radiation toxicity incurred during the treatment of cancer.|
|Bioptigen: non-invasive optical coherence tomography for high-throughput, in vivo imaging of biological systems|
|Biscardia: Clinical-stage pharmaceutical company developing therapeutics for cardiovascular disease.|
|Bright View Technologies: light management products for display applications.|
C2: developing technologies for the expansion and engraftment of Hematopoietic stem cells.
|Caradigm (Formerly: Sentillion): enabling healthcare organizations to meet the challenges associated with identity and access management (IAM).|
|Cellective Therapeutics: research on B-cells, a class of cells in the immune system. Acquired by MedImmune in 2005.|
|Centice: Computational sensing to facilitate the sampling of signals, such as an optical spectrum or image, with maximum efficiency and fidelity.|
|CereNonva: Novel solutions to enhance and restore neurological function.|
Chaperone Therapeutics: developing therapies for diseases like Alzheimer’s, Parkinson’s, Huntington’s, ALS, etc., that are associated with protein misfolding, by restoring the body's natural balance of the protein folding activity.
Cytex Therapeutics: mission is to provide bio-artificial devices to treat orthopaedic diseases and injuries and improve quality of life for patients. The company is focused extensively on developing products to replace or regenerate cartilage and treat osteoarthritis (OA).
Deep Brain Innovations: developing innovative neurodevice technologies to address significant unmet health conditions.
|FibroGen: discovering, developing, and commercializing novel therapeutics for fibrotic disorders, diabetic complications, anemia, conditions associated with tissue damage or injury, cancer, and other areas of unmet medical need.|
|GrassRoots (Acquired by Monsanto): An Agricultural Biotechnology company utilizing a Systems Biology Approach to develop new valuable crop lines for the biofuel, food and industrial markets.|
|HemoSonics: innovative diagnostics to quantify and characterize the hemostatic potential of whole blood and inform appropriate therapy in a variety of clinical settings.|
|Humacyte: a clinical stage company producing biologically based vascular implants.|
|Improved Patients Outcomes, Inc.: Combines CellepathicRx's proven mHealth mobile platform and Duke University's research-backed patient behavioral content, with the focus on improving patient adherence and outcomes|
|Kymeta: products to simplify satellite connections needed for instant broadband service anywhere in the world, including mobile applications such as planes, trains, boats, and automobiles|
|LCMS+: an online software application designed specifically for health care education curriculum management. The functional features of the application include curriculum content management, evaluation management, exam development, patient encounter tracking, clinical skills assessment, scheduling functionality and support for team based learning.|
|Merix Bioscience: RNA-based vaccine technology. Merix merged with Argos Therapeutics in 2004.|
|N30 Pharma (formerly Nitrox, LLC): developing a novel class of disease modifying therapies that preserve intracellular GSNO (S-nitrosoglutathione), a key regulator of organ repair, regeneration, and healing, with a lead program focused on on cystic fibrosis.|
Oncoscope, Inc.: develops proprietary optical imaging systems for guided biopsy in epithelial tissues in the esophagus, colon, lung, cervix, and bladder, where 85% of all cancers start
|Orexigen: pharmaceutical products for the treatment of central nervous system disorders, with an initial focus on obesity.|
|PhaseBio Pharmaceuticals: a clinical-stage biopharmaceutical company committed to developing new products to deliver existing therapeutic agents with greater efficacy and lower side effects, and also manufacturing services for purification for therapeutic proteins and peptides.|
|Precision Biosciences: Patent pending Directed Nuclease Editor(tm) allows production of enzymes capable of producing double-strand breaks at predetermined DNA sites, with a focus on anti-infective therapeutics.|
|Regado Biosciences a public compapany (Nasdaq: RGDO) pioneering a new therapeutic technology with the creation and development of two-component drug systems, each comprising a nuclease-stabilized RNA aptamer that can be controlled directly by its specific and complementary oligonucleotide active control agent. This technology is being applied to injectable antithrombotics (including anticoagulants and antiplatelet agents) in the acute and sub-acute care settings.|
Sentilus: is commercializing a point-of-care diagnostic based on a polymer brush technology.
Southeast TechInventures STI: a technology accelerator for rapid conversion of university scientific breakthroughs into products, services and new technology companies.
STRAD: primary technical focus is the development of signal processing solutions to challenging problems in surveillance systems and sensing applications.
SyneCor: transforming innovative medical device ideas from concept through incubation into synergistic growth corporations.
The Biomarker Factory: promotes the identification and funding of unique proposals that connect the discovery of biomarkers with their utilities in clinical practice. Key areas of expertise include: experimental designs for diagnostic studies, biospecimen collection, assay development, clinical research and treatment practices, and commercialization of intellectual property and technology.
Trimeris: discovery and development of novel treatments for viral diseases. Acquired by Synageva in 2011.
|Trevena: is a drug discovery company focused on developing pharmaceutical products targeting G-protein coupled receptors (GPCRs).|
|Unravel: Tools to enable performance of timely and scalable analytical processing of large datasets which are now a critical ingredient for the success of most organizations.|
|Zumatek: a clinic-ready 3D breast CT system for dedicated breast imaging that allows for full breast and chest wall access while maximizing patient comfort and consequently minimizing patient motion. Scans can be operated independently by a (mammography) technologist, raw image results are packaged in DICOM format, and reconstructions are performed automatically and rapidly.|
|Zenalux Biomedical: developing novel biophotonic-based tools to aid in the diagnosis and treatment of cancer as well as other disease states; the company’s flagship product is the Zenascope, a patent-protected, photonic system that non-destructively measures dominant tissue chromophores (oxygenated hemoglobin, deoxygenated hemoglobin and beta-carotene) as well as changes in cellular morphology and density.|