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Isogenic HCT1116 cell lines with heterozygous or homozygous MLL2 inactivating mutation

HCT 116- MLL2 +/- line (MLL2 heterozygous knockout; two clones)-...


Biomaterial therapy for healing brain tissue after ischemic stroke

Unmet Need Ischemic stroke affects 692,000 patients annually in the...


Transgenic mice harboring CRISPR-based transcriptional activators

CRISPR-based tools for gene regulation have enabled new studies of...


GAD67-GFP mice

This line of transgenic mice expresses GFP in newly generated...


Drd1 a-tdTomato BAC transgenic mouse

Fluorescent transgene (tdTomato) identifies cells with expression of tbe type...


Materials and methods to study nonsyndromic autism due to ANK2 mutation

Duke scientists have developed a first of its kind mouse...


Genetic control of neurol activity in mice conditionally expressing TRPV1

ROSA-stop flox-TRPV1-IRES-ECFP knock-in mice Background strain 129S1/SvlmJ Mice that are...


Tunable elastomer-like polymers for use in soft tissue regeneration and drug delivery

Unmet Need Biodegradable synthetic polymers are often used as scaffolding...


An injectable hydrogel scaffold that delivers gene therapies locally

Unmet Need Gene therapy has applications ranging from tissue engineering...