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Small molecules

Adjuvants to chemotherapeutics in cancer

Value proposition Cancers are often treated with chemotherapies, many of...

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Novel iron chelators that protect cells from oxidative stress

Unmet Need Metal ions play important roles in the proper...

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ABL kinase inhibitors regulate SLC7A11 expression and may treat brain tumors

Value Proposition The Abl kinases, Abl1 and Abl2, are a...

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Novel therapeutic targets in the androgen receptor signaling pathway for prostate cancer

Unmet Need Prostate cancer is the most common malignancy in...

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Treating heart failure with bisphosphonate compositions

Value Proposition The prevalence of heart failure (“HF”) has grown...

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Beta-arrestin inhibition to prevent S1P1 internalization as a treatment for intracranial diseases

Value Proposition Glioblastomas (GBMs) are among the most common and...

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SUMO as a marker of cancer development and target for cancer therapy

Value Proposition Cancer therapy remains challenging, and the production of...

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Targeting fructose metabolism as therapeutics for cancer cells in the liver

Value Proposition Colorectal cancer (CRC) is a common and lethal...

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Abl kinase inhibitors promote lung regeneration after pathogen and chemical-induced injury

Value Proposition Damage to the lung epithelium in response to...

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