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Use of rifaximin and bacterial strains for treating probable neurodegenerative disorders like Alzheimer’s Disease
Unmet Need There is an urgent need to develop novel therapies for neurodegenerative diseases and conditions such as Alzheimer's disease (AD). Ten percent of people over age 65 and up to 50% over age 85…
A method of treating and preventing gastrointestinal disorders
Unmet Need Gastrointestinal disorders such as inflammatory bowel disease, constipation, and intestinal pseudo-obstruction have been estimated to affect more than 40% of adults worldwide. These disorders are often associated with alterations in gut microbiota, which…
Novel regulators of root growth
Value Proposition With growing populations and changing climate, agricultural technologies that enhance crop growth and increase stress tolerance are crucial. Stress tolerance, which includes low soil fertility and drought conditions, are relevant to both crop…
Strengthening a patient’s immune functions to prevent infectious diseases without developing antibiotic resistance
Unmet Need Despite the development of numerous antibiotics over the years, the arms race between humans and emergent antibiotic-resistant microbes remains. More than 2.8 million antibiotic-resistant infections and 35,000 deaths occur in the U.S. each…
Mining microbial genomes for biologically active compounds
Most microbes of importance to human and environmental health are not amenable to experimentation. As a result, we do not know what molecules these microbes use to manipulate their environment- many of which are likely…