Technology A method for producing a gas microbubble comprises subjecting the gas microbubble to isothermal conditions or cooling conditions such that the lipid-containing shell cools at a rate ranging from about 100° C./min. to about 103° C./min., and wherein said subjecting step transforms the lipid-containing shell from a liquid state to a solid state.
- US Patent No.: 6,210,611
Inventor David Needham, Ph.D. Professor, Department of Mechanical Engineering and Material Science Duke University
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