Reducing motion-related artifacts in magnetic resonance imaging

Value Proposition

Magnetic resonance imaging (MRI) is useful in diagnosing a wide variety of diseases and conditions. However, the procedure is highly susceptible to motion-induced artifacts. Existing magnetic resonance imaging protocols largely rely on either breath holding or respiratory gating. However, the gating does not completely eliminate motion-related artifacts, while the breath-holding can be difficult for pediatric patients and some adult patients. Since existing motion artifact reduction methods cannot always completely eliminate motion-related artifacts, a significant subset of patients need to be sedated to complete MRI procedure. The invention enables high-quality body MRI for patients without requiring sedation.

Technology

Researchers at Duke have developed a method of minimizing motion-related artifacts in MRI imaging. The technique can effectively suppress artifacts in data obtained with different accelerated magnetic resonance pulse sequences, k-space trajectories and contrasts. It can be applied to address in-plane motion artifacts in 2D MRI. It can be directly extended to eliminate artifacts induced by both in-plane and through-plane motion in 3D imaging. The procedure has been validated in participants with incessant head tremors.

Advantages

  • Compatible with echo-planar imaging, fast spin-echo imaging, and gradient-echo and spin-echo imaging
  • Can be applied to address motion-related artifacts in 2D and 3D MRI data
  • Effectively suppress motion-related artifacts even for highly challenging cases, such as continual head tremor
  • Eliminates the need for sedation

Duke File (IDF) Number

T-004112

Inventor(s)

  • Chen, Nan-kuei
  • Chu, Mei-Lan
  • Song, Allen

Patents

    • Patent Number: 10,317,499
    • Title: MRI WITH REPEATED K-T -SUB-SAMPLING AND ARTIFACT MINIMIZATION ALLOWING FOR FREE BREATHING ABDOMINAL MRI
    • Country: United States of America

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College

School of Medicine (SOM)