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Targeting the Wnt-beta-catenin Signaling Pathway to Augment the Efficacy of Checkpoint Inhibitor Immunotherapy

This technology is associated with theuse of Wnt-Beta cateniin antagonists to circumvent resistance and enhance the efficacy of currently available immune checkpoint inhibitors in patients with advanced cancer.

Duke File (IDF) Number



  • Hanks, Brent
  • Holtzhausen, Alisha

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School of Medicine (SOM)

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