Linking Ideas to Impact

The Office of Licensing & Ventures (OLV) is the licensing and new venture creation arm of Duke University and the Duke University Medical Center. It's where Duke innovations meet industrial, entrepreneurial, legal and investment markets to create the partnerships necessary to create value and benefit society.

Featured Technology:

Computed Tomography (CT) Simulation using a Digital Phantom

Using state-of-the-art computational modeling techniques, Paul Segars, PhD, develop a series of computerized phantoms that realistically model the human anatomy and cardiac and respiratory motions for medical imaging research. These phantoms, which include both genders, and varying ages, heights, and weights from infancy to adulthood, can serve as a population with which to perform virtual clinical trials in medical imaging. The phantoms are used in our research and by researchers around the world to quantitatively evaluate and improve imaging devices and techniques, optimizing them to produce diagnostic quality images at the lowest possible dose to the patient.
Learn more.

Featured Technology:

Genome Engineering in Skeletal Muscle

The Gersbach lab develops new methods to manipulate the genome for a wide variety of applications. Recent breakthroughs published in Molecular Therapy, PNAS, and Nature Methods that have been highlighted in news outlets from Science to The New York Times underscore the importance of Gersbach's accomplishments in advancing the potential for gene therapy to treat disease. Using methods including viral delivery, gene repair, and gene regulation, the Gersbach lab has successfully advanced innovative technologies like TALE- and CRISPR/Cas9-based nucleases and transcription factors to reprogram the human genome at will. The results bring the possibility of clinically useful therapies for disabling and fatal diseases like Duchenne's Muscular Dystrophy, and enable other areas such as ag/bio applications. Learn more.

Featured Technology:

Radiation Dosage Measurement System using Nano Scintillators

Dr. Therien synthesizes compounds, nanoscale structures, and materials with unusual ground- and excited- state characteristics. A subset of these compositions form the basis of nanoscale detectors with a wide variety of applications including in radiation detection, in vivo imaging, and high sensitivity in vitro diagnostics. His most recent invention involving nanoscale structures for radiation detection has applications in clinical, commercial, and military dosimetry and is currently funded to perform first-in-human studies with a grant from the Coulter Translational Research Partnership and project leadership from the Duke Translational Research Institute. Dr. Therien's technology is available for licensing and is currently raising capital. Learn more.

Featured Technology:

Ophthalmic Drug Delivery Device and Methods of Use

Dr. Molly Walsh and Duke Ophthalmology's device advances to first-in-human pilot study to deliver drugs to the front of the eye. By temporarily occluding venous outflow, the device allows retrograde injection through the episcleral veins. Dr. Walsh, an ophthalmologist has developed a novel low-cost disposable device that allows physicians to easily deliver medications to the front of the eye. The device has the potential to depot drugs in the front of the eye for long-term reduction of intraocular pressure. This innovation, funded by Duke's Coulter Translational Research Partnership grant, has the potential to dramatically improve patient compliance and outcome with existing and novel therapeutics in glaucoma. Learn more.

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Internship Opportunities


Are you interested in how new inventions become products and new companies? Get real-world experience as an Intern at Duke's Office of Licensing & Ventures. The position includes performing computer and journal searches to determine how Duke inventions compare to work at other schools/companies, writing reports based on your findings, and working with OLV staff to find potential licensing partners. There may also be some administrative copy/file tasks as needed. The position requires a minimum of 10 hours per week and a maximum of 19 hours per week. We are looking for candidates with excellent writing and computer search skills. Science/chemistry background is a plus. Only enrolled undergrad or graduate students may apply.

If you are interested in applying, please contact Kathy Beckett at 919-681-7578 or email your resume to kathy.beckett@duke.edu

Duke University and Health System endorses the University Good Licensing Practices: Learn more.