Chaperone Therapeutics


Launched:

2009

Management:

Dennis Thiele

Duke Inventor(s):

Dennis Thiele

Therapies for diseases like Alzheimer’s, Parkinson’s,associated with protein misfolding.

Chaperone Therapeutics is developing frontline therapies to address diseases of protein misfolding: the underlying causes of neurodegenerative and other rare diseases. Our therapeutic approaches elevate the natural protein folding and stress protection mechanisms to prevent protein misfolding and the ensuing cell dysfunction and death. Chaperone’s unique drug discovery platforms, broad knowledge in small molecule optimization and expertise in animal models of protein misfolding disease and clinical evaluation propel our therapeutic discovery programs forward.

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