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A novel adjuvant capable of specifically activating the adaptive immune response

A composition for eliciting an immune response to an immunogen comprises an immunogen in combination with a mast cell membrane activator such as compound 48/80. Any suitable immunogen may be employed, such as an antibody-inducing determinant, a lipid, a peptide (e.g., an antibody-inducing peptide), a carbohydrate, an immunogen derived from a virus or cancer cell, etc. Methods of use are also described.

Duke File (IDF) Number

T-002181

Inventor(s)

  • Pizzo, Salvatore
  • Abraham, Soman
  • Hart, Justin
  • McLachlan, James
  • Staats, Herman "Herman"

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College

School of Medicine (SOM)

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